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Updated: Jan 10, 2026

Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices
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Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices

Published on: July 14, 2010

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胆固醇突触可塑性塑造了对tau的弹性和脆弱性

Kate M Onuska, Lauren A Devito, Hayley Rc Shanks

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    胆固醇神经元通过增加囊泡性乙胆载体 (VAChT) 水平来适应早期阿尔茨海默氏症的病理,这是与保存认知相关的反应. 这种突触可塑性突出显示了在前症状阿尔茨海默氏症中弹性和脆弱性机制.

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