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Updated: Jan 10, 2026

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
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原子的TCR-连接体相互作用指导记忆T细胞分化

Aoi Akitsu1,2,3, Kemin Tan4, Robert J Mallis1,2,3,5

  • 1Laboratory of Immunobiology, Dana-Farber Cancer Institute; Boston, MA 02115, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

记忆T细胞提供适应性免疫力. 这项研究揭示了T细胞受体 (TCR) 信号偏差如何决定CD8+ T细胞是否成为中央 (TCM) 或效应器 (TEM) 记忆细胞,从而影响病原体反应.

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