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Updated: Jan 10, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
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在基因毒性压力后,DAF-16/FOXO保持了基因组完整性

Umanshi Rautela1, Oviya Devendran1, Gautam Chandra Sarkar1

  • 1Molecular Ageing Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

福克斯转录因子DAF-16通过激活C. elegans的DNA损伤反应 (DDR) 基因来保护基因组的完整性. 这一途径对于预防衰老和确保跨世代遗传稳定性至关重要.

关键词:
对DNA损伤的反应反应在FOXO/DAF-16中使用.细菌线的生殖线.胰岛素的信号传递方式这就是所谓的 soma soma soma.

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