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线粒体向的HDAP2保护了视网膜质细胞,并增加了DBA/2J小鼠的压力耐受性

Margaret A MacNeil1, Widnie Mentor1, Alexander Birk1,2

  • 1Department of Biology, York College of the City University of New York, Jamaica, NY 11451.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

一种新型的,HDAP2,通过稳定线粒体,显著增加了视网膜质细胞 (RGC) 在青光眼的小鼠模型的存活率. 这为玻璃眼病患者提供了潜在的新疗法,即使是那些正常或耐火眼内压 (IOP) 患者.

关键词:
在DBA/2J小鼠中.在HDAP2中,HDAP2是指HDAP2.玻璃眼 glaucoma 玻璃眼 玻璃眼 玻璃眼 玻璃眼眼内压力 眼内压力线粒体功能障碍 线粒体功能障碍神经保护神经保护视网膜质细胞是视网膜质细胞

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