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Updated: Jan 10, 2026

Monitoring the Effect of Osmotic Stress on Secretory Vesicles and Exocytosis
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Monitoring the Effect of Osmotic Stress on Secretory Vesicles and Exocytosis

Published on: February 19, 2018

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葡萄糖皮质类药物通过激活nSMase2来调节小细胞外囊泡 (sEV) 的释放

Mia Burke1,2, Clarissa Waites2,3

  • 1Pathobiology and Mechanisms of Disease Graduate Program, Columbia University Irving Medical Center, New York, NY.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

慢性压力会增加葡萄糖皮质醇 (GCs),加速阿尔茨海默病 (AD). GCs通过线粒体损伤和nSMase2激活刺激神经元小细胞外囊 (sEV) 释放,从而导致AD病理.

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