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Updated: May 5, 2026

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
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Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry

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基因传递由脊柱可降解RAFT共聚物介导

Prajakatta B Mulay, D Christopher Radford, Brayan Rondon

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    开发脊柱可降解的阴离子共聚合物显著提高了基因传递效率和生物相容性. 这些新型聚合物在低N/P比率下,在不增加细胞毒性的情况下,在转染中显示出10倍的改善.

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    Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery

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    Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

    Site-Targeted Drug Delivery Systems: Polymeric Carriers

    Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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