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Updated: Jan 10, 2026

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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Published on: February 28, 2019

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细胞因子受体协会的几何调节调节合成激动体信号传递

Marc Expòsit1,2,3, Mohamad Abedi1,2, Aditya Krishnakumar1,2

  • 1Department of Biochemistry, University of Washington, Seattle, WA, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

研究人员开发了一个新的蛋白质设计平台来控制细胞因子受体几何. 这允许精确调整免疫细胞信号通路和功能结果,从而实现可编程的免疫调制.

关键词:
细胞信号传递 细胞信号传递细胞因子工程 细胞因子工程蛋白质设计 蛋白质设计合成生物学 合成生物学

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