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Updated: Jan 10, 2026

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在分裂前的TCF1下降决定了长期的CD8 T细胞命运.

Natalie R Favret1, Maider Astorkia2,3, Melissa M Wolf1

  • 1Department of Medicine, Division of Hematology and Oncology, Department of Pathology, Microbiology, and Immunology, Vanderbilt School of Medicine, Nashville, TN, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

T细胞因子1 (TCF1) 在CD8 T细胞分裂之前迅速下降,然后反弹,影响长期的效应细胞命运. 这种动态调节作为免疫反应的关键检查点.

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