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Updated: Jan 10, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
04:41

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

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多种祖先的转录基因组广泛关联研究揭示了阿尔茨海默氏病的共同和特定人口的遗传效应

Xinyu Sun1,2, Makaela Mews3,2, Nicholas R Wheeler1,2

  • 1Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

这项研究表明,在不同人群中分析阿尔茨海默病 (AD) 遗传学可以改善基因发现. 多种人群分析发现了新的AD风险变体,并强调需要更广泛的队列纳入.

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Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

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