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Updated: Jan 10, 2026

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
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Published on: April 11, 2019

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中心分子不稳定驱动染色体损伤和系统性硬化症中自身抗原暴露

Azait Imtiaz1, Mohammad Waseem1, Hudson O'Neill1

  • 1Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, 35233, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

布莱俄米辛会损害中间体,导致染色体不稳定性和系统性硬化症 (SSc) 的免疫激活. 这种损伤涉及活跃的中间体,并导致错位的染色质,可能解释SSc自身抗体的特异性.

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