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Updated: Jan 10, 2026

Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies
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在流感的广泛演变中的脆弱性广泛中和抗体

Katrine E Dailey1, Yiquan Wang1, Qi Wen Teo1,2

  • 1Department of Biochemistry, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

CR9114抗体向流感血质素 (HA) 干,但难以结合多种菌株. 这项研究揭示了突变,限制了它对流感A和B病毒的广泛交叉反应,解释了疫苗开发的挑战.

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