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Updated: Jan 10, 2026

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卡皮卡异型的功能差异解释了神经疾病中不同组织的脆弱性

Hamin Lee1,2,3, Esmeralda Villavicencio Gonzalez1,2,3, Elias M Rivera2,3

  • 1Program in Genetics and Genomics, Baylor College of Medicine, Houston, TX 77030, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

卡皮卡 (CIC) 蛋白质有两个异构体,CIC-L和CIC-S,它们与不同的Ataxin-1 (ATXN1) 对应物相互作用. 这种异形-平行类相互作用解释了神经退行性疾病的区域脆弱性,例如1型脊髓小脑动症 (SCA1).

关键词:
在 ATXN1 的位置上.ATXN1LL 在线播放在 CIC CIC 中,您可以在 CIC CIC 中查看更多信息.卡皮克瓦 (Capicua) 是一个古老的植物.形合金是一种合金.这种异形异形是什么?神经退行症的神经退行症神经发育的神经发育一个模拟模拟器.蛋白质复合体是一种蛋白质复合体.

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