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Updated: Jan 10, 2026

Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules
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在ALS中,KIF5A结合RNA调节突触mRNA定位和压力颗粒

Phuong Le, Neeraj K Lal, Shuhao Xu

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    素电机KIF5A直接结合mRNA,调节突触蛋白质的运输和神经元的功能. 与ALS相关的KIF5A突变破坏了这一过程,导致突触功能障碍和应激反应受损.

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