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Updated: Jan 10, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
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在MPER/脂质体疫苗中,异种免疫调节了辅助和MPER部分之间的B细胞表位竞争

Rafiq Ahmad Khan, Junjian Chen, Luke Donius

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    异质增强通过改善B细胞亲和力和减少竞争来增强对HIV-1保存的MPER区域的免疫反应. 这一策略对于开发针对HIV-1等可变病毒的广泛中和抗体 (bnAbs) 至关重要.

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