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Updated: Jun 18, 2026

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations
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scFPC-DE:通过功能性主要组件分析沿单细胞轨迹进行强大的差异表达分析

Ricardo J López Candelaria1, Yu Qian2, Fang Chen3

  • 1Department of Biostatistics and Computational Biology, University of Rochester, Rochester, NY 14642, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

我们开发了scFPC-DE,这是一种分析单细胞RNA测序数据中的基因表达变化的新方法. 它通过计算基因表达模式和减少假阳性来提高准确性,从而导致更具生物相关性的发现.

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相关概念视频

Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...