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Updated: Jan 10, 2026

Functional Characterization of Na+/H+ Exchangers of Intracellular Compartments Using Proton-killing Selection to Express Them at the Plasma Membrane
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Published on: March 30, 2015

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在人体/化物共载体 (NIS) 中工程基质选择性.

Alejandro Llorente-Esteban, Haswitha Sabbineni, Kendra Hoffsmith

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    工程化Na+/I−共载体 (NIS) 突变物选择性地运输氧离子,而不是化物. 这允许使用放射性同位素进行向癌症治疗,同时保护甲状腺,扩大NIS应用范围超出甲状腺癌治疗范围.

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