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Updated: Jan 10, 2026

Assessing Cardiomyocyte Subtypes Following Transcription Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts
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Assessing Cardiomyocyte Subtypes Following Transcription Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts

Published on: March 22, 2017

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剂量敏感的RBFOX2自我调节通过成熟转录基因组促进心肌细胞分化

Mengmeng Huang, Feria A Ladha, Yunxia Wang

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    减少RNA剪接调节器RBFOX2水平会损害心肌细胞分化,导致先天性心脏病 (CHD). 这发生在受损的自我调节和改变的基因拼接过程中,影响心脏的发育和功能.

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