COVID-19相关的粘性菌根症:在回顾性队列研究中确定死亡率预测因素
Zahra Ghavami1, Mahboubeh Haddad1, Fereshte Sheybani1
1Department of Infectious Diseases and Tropical Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Open forum infectious diseases
|November 24, 2025
概括
与COVID-19相关的粘膜 (CAM) 是一种严重的并发症. 升高的CRP水平预测死亡率,而长期的抗真菌治疗和可纳使用改善了CAM患者的生存率.
科学领域:
- 传染性疾病 传染性疾病
- 菌类学 菌类学是指菌类学.
- 临界护理医学 临界护理医学
背景情况:
- 与COVID-19相关的粘膜 (CAM) 是COVID-19的一种严重并发症.
- 免疫抑制治疗加剧了CAM风险.
- 了解CAM的临床结果和死亡率预测因素至关重要.
研究的目的:
- 评估成人CAM患者的临床结果.
- 为了确定CAM中死亡率的预测因素.
- 为改善患者存活率提供治疗策略的信息.
主要方法:
- 在伊朗的一个主要推中心进行的回顾性队列研究.
- 从COVID-19大流行开始到第五波,收集的数据.
- 对临床特征,并发病,治疗和生存率的分析.
主要成果:
- 糖尿病 (76.5%) 和皮质类固醇使用 (90.1%) 是常见的. 一年生存率为50.6%.
- 升高的CRP水平 (P=.001) 预测死亡率增加.
- 口腔亡 (HR: 2.12) 是一个危险因素,而较长时间的抗真菌治疗和可纳使用 (HR: 0.16) 降低了死亡率.
结论:
- 早期诊断和及时,长期治疗对于CAM患者至关重要.
- 升高的CRP识别出患有较高死亡风险的患者.
- 需要进一步的研究来完善风险分层和优化CAM的治疗方案.
相关概念视频
Fungal Group Zygomycota
961
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
961
Factors Affecting the Risk of Infection
13.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.2K


