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Updated: Jul 22, 2026

Isolation of Leukocytes from the Human Maternal-fetal Interface
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通过CXCL9/STAT1/ZEB1/CCL2轴的M1巨细胞和热囊细胞之间的相互激活促进了反复的自发流产

Sisi Yan1, Xiang Wang1, Qiuji Wu1

  • 1Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University, Wuhan, China.

Frontiers in immunology
|November 24, 2025
PubMed
概括

在复发性自发性流产 (RSA) 中,M1巨细胞通过释放CXCL9来抑制 trofhoblast 功能,CXCL9是这种免疫相关妊娠并发症的关键因素. 这种相互作用突出了影响早期怀孕健康的新途径.

关键词:
在CXCL9中使用.在EMT中,EMT是EMT.在M1-Mφ中,M1-Mφ是M1-Mφ.迁移和入侵的情况.经常发生的自发性流产.热囊细胞 热囊细胞

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