优化静脉血栓塞栓症在阿基里斯肌破裂中的预防:对当前证据和协议建议的系统审查
Mohamed Hashem1, Mohamed Elbeshbeshy2, Mohamed Khalafallah3
1Orthopaedics, Frimley Health NHS Foundation Trust, London, GBR.
Cureus
|November 24, 2025
概括
阿基勒斯肌破裂患者需要个性化静脉瘤预防. 高风险人群受益于抗凝药,而低风险患者可能会使用早期动员和机械方法.
科学领域:
- 整形外科 整形外科 整形外科
- 血管医学 血管医学
- 运动医学 运动医学
背景情况:
- 由于体育活动的增加,阿基里斯肌破裂 (ATR) 的发生率正在上升.
- 静脉血栓塞栓症 (VTE) 是ATR患者的一个重大并发症.
- 目前对ATR的VTE预防方案需要基于证据的改进.
研究的目的:
- 评估在ATR治疗期间预防VTE的抗凝血疗效.
- 为ATR患者建立一个基于证据的VTE预防方案.
- 引导临床实践,以优化ATR中的VTE预防.
主要方法:
- 在主要数据库 (PubMed,Scopus,WoS,Cochrane) 进行全面的文献搜索.
- 八项涉及1199名ATR患者的研究的定性综合.
- 分析重点关注VTE预防,并发症和临床结果,考虑研究质量.
主要成果:
- 使用TRiP ((cast) 等工具进行风险分层对ATR患者至关重要.
- 高风险患者显示药理学预防 (LMWH或里瓦罗克萨班) 显著有益,持续≥28天.
- 低风险患者通过早期动员和机械预防有效地管理了静脉瘤风险.
结论:
- 建议在ATR中采取个性化的方法来预防VTE.
- 结构化的风险评估确保了有针对性和有效的预防性干预措施.
- 需要进一步的研究来优化预防治疗的持续时间和方案,特别是对于低风险患者.
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