使用SPHERE绩效指标恢复后重度急性营养不良的复发负担:系统性审查和元分析
Fassikaw Kebede Bizuneh1, Birtukan Gizachew2, Tsehay Kebede3
1College of Medicine and Health Science Debre Markos University Debre Marqos Ethiopia.
Health science reports
|November 24, 2025
概括
在埃塞俄比亚治疗严重急性营养不良 (SAM) 的儿童中,近五分之一的儿童复发,超过了SPHERE标准. 诸如MUAC排放标准和粮食不安全等因素预测复发,需要修订指南和支持.
科学领域:
- 公共卫生 营养 公共卫生 营养
- 流行病学 流行病学
- 全球健康 全球健康
背景情况:
- 埃塞俄比亚严重急性营养不良 (SAM) 复发因地区冲突,并发病症和高自我排放率而加剧.
- 估计SAM复发的负担对于有效的公共卫生干预至关重要.
研究的目的:
- 估计埃塞俄比亚严重急性营养不良 (SAM) 的复发负担.
- 通过系统性审查和元分析 (SRMA) 使用SPHERE绩效指标来评估SAM复发.
主要方法:
- 按照PRISMA指南进行系统审查和元分析 (SRMA).
- 包括8项涉及4878名参与者的研究,使用JBI检查清单进行质量评估.
- 超回归分析以估计聚合复发负担并确定预测因素,通过科克兰的Q和I2统计评估异质性.
主要成果:
- 综合国家SAM复发负担为19.4%,区域差异很大 (阿姆哈拉: 26.9%,南部: 10.52%).
- 恢复,消耗和死亡率分别为79.17%,4.15%和5.84%.
- 上半臂周长 (MUAC) ≥125毫米排放标准 (HR 3.6) 和家庭粮食不安全 (HR 6.33) 是SAM复发的重要预测因素.
结论:
- 埃塞俄比亚的SAM复发率明显超过了SPHERE绩效指标.
- 目前的MUAC排放标准需要重新评估和标准化.
- 加强营养教育,家庭粮食援助和持续跟踪对SAM治疗的儿童至关重要.
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