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Updated: Jan 10, 2026

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在癌症中量化复制应激,而不会导致扩散的混

Philipp Jungk1, Maik Kschischo1

  • 1Institute for Computer Science, University of Koblenz, Koblenz, Rhineland-Palatinate, Germany.

Cell stress
|November 24, 2025
PubMed
概括

我们开发了一种新的基因表达特征 (TRSS),以准确地测量复制应激 (RS),独立于细胞增殖. 这种签名揭示了RS和DNA修复途径之间的联系,特别是非同类末端结合 (NHEJ).

关键词:
细胞的增殖细胞的增殖.染色体的不稳定性基因表达签名 基因表达签名不匹配的维修 维修不匹配的维修不同类的末端连接.复制压力是复制的压力.

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