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Updated: Jan 10, 2026

In Vitro Cultivation Techniques for Modeling Liver Organogenesis, Building Assembloids, and Designing Synthetic Tissues using Human Cell Lines
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FKBP9增强IGF2BP1介导的m6的识别,促进肝细胞癌的进展

Facai Yang1, Anfeng Si2, Cheng Chi1

  • 1Hepato-pancreato-biliary Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.

JHEP reports : innovation in hepatology
|November 24, 2025
PubMed
概括

通过增强m6A修饰转录的识别,稳定MYC和PDGFB,FKBP9促进肝细胞癌 (HCC). FKBP9-IGF2BP1通路是HCC的潜在治疗标.

关键词:
结合FK506的9蛋白 (FKBP9) 是一种结合FK506的9蛋白.肝细胞癌 (HCC) 是一种肝细胞癌.胰岛素样生长因子2的mRNA结合蛋白1 (IGF2BP1)N6-甲基氨酸 (m6A) 的修改在mRNA的稳定性上.

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