慢性史蒂文斯-约翰逊综合征的手术治疗
Aastha Garg1, Abha Gour2, Nidhi Chauhan1
1Department of Cornea & Anterior Segment, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Frontiers in medicine
|November 24, 2025
概括
史蒂文斯-约翰逊综合征 (SJS) 可以导致严重的眼睛问题. 本综述详细介绍了治疗策略,如移植和手术,以治愈慢性SJS患者的眼睛表面并恢复视力.
科学领域:
- 眼科医生 眼科 眼科
- 皮肤病学 皮肤病学
- 再生医学是一种再生医学.
背景情况:
- 史蒂文斯-约翰逊综合征 (SJS) 是一种严重的粘膜皮肤疾病.
- 慢性眼部并发症是SJS的常见后果.
- 管理需要一个多学科的方法.
研究的目的:
- 审查SJS的病理生理学和眼部后果.
- 讨论基于证据的眼球表面稳定和视觉恢复策略.
- 概述慢性眼部SJS的分阶段管理计划.
主要方法:
- 对病理生理学和长期眼部后果的审查.
- 讨论干预措施:点性阻塞,粘膜移植 (MMG),胎膜移植 (AMT).
- 探索先进的选择:培养口腔粘膜上皮移植 (COMET),小唾液腺移植 (MSGT),痕内皮纠正和视觉康复.
主要成果:
- 点性闭塞,MMG,AMT,COMET和MSGT是眼睛表面管理的关键干预措施.
- 手术纠正伤内恢复了眼的对齐.
- 通过白内障手术或角膜假体进行视觉康复需要仔细规划.
结论:
- 一个量身定制的,分阶段的管理计划对于慢性眼部SJS至关重要.
- 专注于表面保护,结构纠正和视觉恢复可以改善患者的治疗结果.
- 多学科护理可以提高SJS患者的生活质量.
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