童年不良经历与母乳养开始和持续时间之间的关联:巴基斯坦的一项纵向出生队列研究
Emilie E Egger1, Paola Bojorquez-Ramirez2, Sarah C Haight3
1University of Pennsylvania Perelman School of Medicine.
Research square
|November 24, 2025
概括
在巴基斯坦农村地区,不良童年经历 (ACE) 与3个月和6个月的纯母乳养率较低有关. 这凸显了针对ACE的干预措施的必要性.
科学领域:
- 孕产妇和儿童的健康
- 健康中的心理社会因素
- 全球健康差异的差异
背景情况:
- 儿童不良经历 (ACE) 与各种健康结果有关,关于它们对母乳养的影响有不一致的证据.
- 低收入和中等收入国家 (LMICs) 面临着重大的母亲和婴儿健康挑战,在这些国家,母乳养可以提供保护性益处.
- 关于ACEs对LMICs母乳养开始和持续时间的具体影响的研究有限.
研究的目的:
- 在巴基斯坦农村地区调查母亲ACE和母乳养开始之间的关联.
- 检查母亲ACE和产后3个月和6个月的纯母乳养之间的关系.
主要方法:
- 来自巴基斯坦巴赫潘队列研究的18-45岁的869名女性的横截面分析.
- 用多变量修改的日志-波松回归模型来评估ACE暴露与母乳养结果之间的关系.
- 模型根据已知的混因素进行调整,以确保可靠的发现.
主要成果:
- 超过一半 (55.2%) 的参与者报告至少有一次ACE.
- 在患有ACE和没有ACE的妇女之间,母乳养开始率没有显著差异.
- 患有ACE病史的女性在产后3个月 (RR=0.8) 和6个月 (RR=0.8) 完全母乳养的可能性较低.
结论:
- ACE似乎会影响纯母乳养率,这表明潜在的长期影响.
- 了解ACE和母乳养之间的联系对于开发有针对性的干预措施至关重要.
- 干预措施应旨在预防或减轻ACE对母亲和婴儿健康结果的负面影响.
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