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Updated: Jan 10, 2026

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
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Published on: March 28, 2025

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由JAK抑制剂破坏代谢许可限制了CD8 T细胞激活和效应器功能

Luisina Inés Onofrio1, Carolina Abrate1, Ingrid Strusberg2

  • 1Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, Universidad Nacional de Córdoba (UNC), Córdoba, Argentina.

Research square
|November 24, 2025
PubMed
概括

简氏激酶抑制剂 (JAKis) 通过破坏其新陈代谢和信号通路,损害CD8 T细胞功能. 这项研究解释了JAKis如何在患有自身免疫性疾病的患者中增加感染风险.

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