约旦儿童的炎症性肠病:一个三级中心的体验
Hala Almomani1, Ayah Alsmadi2, Nicole Issi1
1Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Pediatric gastroenterology, hepatology & nutrition
|November 24, 2025
概括
约旦的儿科炎性肠病 (IBD) 显示克罗恩病比性结肠炎更常见. 有限的生物接入需要改进的治疗方法和国家IBD注册表,以改善儿科IBD护理.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 炎症性肠道疾病研究研究
- 临床流行病学 临床流行病学
背景情况:
- 儿科炎症性肠病 (IBD) 在诊断和管理方面存在独特的挑战.
- 了解IBD的区域差异对于全球健康洞察至关重要.
- 约旦儿科IBD数据有限,需要进行本地研究.
研究的目的:
- 描述约旦儿科IBD的临床特征,亚型,实验室发现和结果.
- 将约旦儿科IBD趋势与全球和区域数据进行比较.
- 确定该地区儿童IBD管理的具体需求和挑战.
主要方法:
- 在约旦大学医院 (2015-2022) 对儿科IBD患者 (年龄<18) 病历的回顾性审查.
- 使用修订的波尔图标准进行诊断确认.
- 分析患者的人口统计,临床表现,疾病行为,实验室标志物和治疗方式.
主要成果:
- 31名儿科IBD患者 (61.3%男性) 平均年龄为8.7岁时被诊断出IBD.
- 克罗恩氏病 (51.6%) 在性结肠炎 (29.0%) 上占主导地位;38.7%的人患有非常早期发病的IBD (VEO-IBD).
- 常见的症状包括腹和腹痛;贫血很普遍 (58.1%),CRP/ESR升高超过60%.
结论:
- 在这个约旦队列中,儿童克罗恩病比性结肠炎更为普遍.
- 观察到对生物疗法的获取有限,治疗频繁升级.
- 需要加强治疗策略和建立国家IBD注册表.
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