休息的右心室功能在pectus excavatum:哈勒指数和年龄是否重要?
Jungsuk Choi1, Gongmin Rim2, Seha Ahn1
1Department of Thoracic and Cardiovascular Surgery, The Catholic University of Korea, Eunpyeong St. Mary's Hospital, Seoul, Republic of Korea.
Frontiers in surgery
|November 24, 2025
概括
哈勒指数 (HI) 和患者年龄不会显著影响右心室 (RV) 缩功能在患有乳房挖掘 (PE) 的患者. 这表明功能评估,而不仅仅是解剖学测量,对于评估PE患者至关重要.
科学领域:
- 心脏病学 心脏病学
- 胸部外科手术 胸部外科手术
- 儿童心脏病学 儿童心脏病学
背景情况:
- 挖掘性乳房 (PE) 可以压缩胸内结构,可能影响右心室 (RV) 功能.
- 哈勒指数 (HI) 量化了PE严重程度,但其与RV功能的相关性尚不清楚.
研究的目的:
- 调查哈勒指数 (HI) 和患者年龄与PE患者静止RV缩功能之间的关联.
- 为了确定HI或年龄是否预测PE患者的RV功能障碍.
主要方法:
- 对67名经过手术纠正的PE患者进行了回顾性队列研究,并采用了手术前心声学数据.
- 通过分数面积变化 (FAC) 和三环状平面缩外流 (TAPSE) 评估RV功能.
- 统计分析包括相关性,子组,回归和ROC分析,按HI严重程度和年龄分层.
主要成果:
- 无论是HI还是年龄都没有与FAC或TAPSE显著相关.
- 亚组和回归分析证实HI和年龄并不能预测RV缩功能受损.
- ROC分析表明,年龄对减少的FAC的歧视力很差.
结论:
- 在PE患者中,休息RV缩功能不受HI或年龄的显著影响.
- 临床评估应包括功能性评估,而不仅仅是解剖学指标,如手术决策的HI.
相关概念视频
Cardiomyopathy III: Hypertrophic Cardiomyopathy
378
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
378
Mitral Regurgitation I: Introduction
392
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
392


