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Updated: Jan 10, 2026

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

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跨祖先多基因风险评分提高了多民族队列中阿尔茨海默病风险预测

Meri Okorie1,2,3,4, Caroline Jonson5,3,6,7,8, Alexis P Oddi5,3

  • 1UCSF School of Pharmacy and the UCSF School of Medicine, University of California, San Francisco, San Francisco, USA.

medRxiv : the preprint server for health sciences
|November 24, 2025
PubMed
概括

开发交叉祖先多基因风险评分 (PRS) 可以改善不同人群中阿尔茨海默病 (AD) 的预测. 这项研究强调了需要包括性的遗传数据,以提高AD-PRS跨祖先的可传输性.

关键词:
这是一个AD-PRS.阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.多基因风险评分多基因风险评分.人口遗传学 人口遗传学

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