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Updated: Jan 10, 2026

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
03:08

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization

Published on: October 3, 2025

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一个伪时间依赖的TWAS框架识别了沿细胞发育路径的疾病基因

Rui Cao, Chunlin Li, Erjia Cui

    medRxiv : the preprint server for health sciences
    |November 24, 2025
    PubMed
    概括

    我们开发了伪时间依赖的转录组全相关性研究 (pt-TWAS) 来分析在连续细胞发育过程中对疾病风险的基因影响. 这种方法增强了统计能力,并确定了B细胞急性淋巴细胞白血病等疾病的因果细胞阶段.

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