在3个低收入和中等收入国家,早期生活逆境与内化和外化行为的关联
Sheri-Michelle Koopowitz1, Richard Shadwell2,3, Nadia Hoffman1
1Neuroscience Institute, Faculty of Health Sciences, University of Cape Town.
medRxiv : the preprint server for health sciences
|November 24, 2025
概括
早期生活中的逆境与来自低收入和中等收入国家的儿童的行为问题有关. 关联因队列而异,在年幼的儿童和特定地区的影响更为强烈.
科学领域:
- 儿童心理学 儿童心理学
- 全球健康 全球健康
- 发展流行病学发展流行病学.
背景情况:
- 生命早期的逆境 (ELA) 是一个已知的风险因素,用于内部化和外部化高收入环境中的行为.
- 在低收入和中等收入国家 (LMICs) 对ELA对儿童行为影响的概括性仍未得到充分研究.
研究的目的:
- 通过三个LMIC群体,调查ELA与儿童内化/外化行为之间的关联.
- 探索这些关联是如何根据孩子的年龄,性别和特定队列背景而有所不同.
主要方法:
- 来自三个LMIC群体 (BHRC,SPRING,DCHS) 的数据汇总,涉及2420名7-10岁儿童.
- 通过第一个24个月的累积指数和儿童行为通过强项和困难问卷 (SDQ) 评估ELA.
- 采用普通最小平方回归,对共变量进行调整和对相互作用进行测试,由于测量非不变性而进行队列内分析.
主要成果:
- ELA与更高的SDQ总分,内部化和外部化行为在整个样本中显著相关.
- 协会在巴西高风险队列 (BHRC) 中最强,在SPRING和DCHS队列中减弱.
- 逆境行为联系在年轻儿童中更为明显,并且在研究的LMIC群体中存在显著差异.
结论:
- 在全球南方群体中,早期生活逆境和精神病理学之间存在明显的关联.
- 这些协会的重要背景变化凸显了区域因素在LMICs中的重要性.
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