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相关概念视频

Somatosensation01:33

Somatosensation

42.9K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
42.9K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

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The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
6.8K

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相关实验视频

Updated: Jan 10, 2026

Design and Use of an Apparatus for Presenting Graspable Objects in 3D Workspace
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Design and Use of an Apparatus for Presenting Graspable Objects in 3D Workspace

Published on: August 8, 2019

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针对脊髓损伤后皮质内脑机界面的最佳掌握相关皮质区域.

Tyler R Johnson, Crispin Foli, Emily C Conlan

    medRxiv : the preprint server for health sciences
    |November 24, 2025
    PubMed
    概括

    这项研究优化了脑电脑接口 (BCI) 电极放置,以使用先进的成像和3D建模来对四肢的掌握解码进行优化. 该方法成功地确定了高保真度手臂和手部运动解码的最佳位置.

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    Assessing Corticospinal Excitability During Goal-Directed Reaching Behavior
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    Design and Use of an Apparatus for Presenting Graspable Objects in 3D Workspace
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    Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
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    科学领域:

    • 神经科学是一个神经科学.
    • 生物医学工程 生物医学工程
    • 康复医学 康复医学 康复医学

    背景情况:

    • 脊髓损伤 (SCI) 经常导致,需要先进的辅助技术.
    • 脑机界面 (BCI) 提供了一种潜在的途径,通过解码神经信号来恢复功能.
    • 优化皮质内电极放置对于有效的掌握相关电机解码至关重要.

    研究的目的:

    • 为了完善内皮层微电极阵列植入部位的抓取解码.
    • 将解剖学,功能和血管成像与3D手术建模相结合,以实现精确的准.
    • 为了确定手术上可行的位置在SCI的个人掌握网络内.

    主要方法:

    • 在一个患有C5四肢的参与者身上利用了解剖学,扩散权重和功能性MRI (fMRI).
    • 使用Quicktome软件集成结构连接和功能激活数据.
    • 开发了一个3D打印模型用于术前规划和模拟电极定位.
    • 在试图移动过程中使用术后神经数据验证了电极放置.

    主要成果:

    • 鉴定了前额内区域 (AIP),腹前运动皮层 (PMv) 和下额 (IFG) 中与抓取相关的显著激活.
    • 由于与运动皮层的强烈连接和明显的功能激活,选择了AIP.
    • 选择了PMv的手术可访问的6v和6r子区域,而不是后部IFG.
    • 在植入后解码手臂和手的动作方面取得了96%的准确性.

    结论:

    • 结合MRI,fMRI,连接和3D建模的多模式方法优化了皮质内电极的放置.
    • 展示了一种有效的方法,用于识别的个体中可行的掌握网络植入物位置.
    • 这是朝着开发BMI系统来恢复SCI患者上肢功能迈出的关键一步.