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Updated: Jan 10, 2026

Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer
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Published on: January 17, 2025

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瘤NLRP3放大通过抑制MHC I类表达促进免疫疗法抵抗

Bala Theivanthiran, Nagendra Yarla, Kaylee Villareal

    medRxiv : the preprint server for health sciences
    |November 24, 2025
    PubMed
    概括

    NLRP3炎症酶途径通过抑制MHC I类表达来驱动免疫疗法抵抗. 抑制NLRP3可以恢复抗瘤免疫力,并在临床前癌症模型中克服耐药性.

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