由于转移性黑色素瘤导致的肝衰竭:一个病例报告
Viktor Domislovic1, Vibor Sesa2, Iva Kosuta3
1Department of Gastroenterology and Hepatology, University Hospital Centre Zagreb, Zagreb 10000, Croatia.
World journal of clinical cases
|November 24, 2025
概括
转移性黑色素瘤可以导致急性肝衰竭 (ALF),模仿其他疾病. 早期诊断透性黑色素瘤对于适当的治疗至关重要,即使没有先前的癌症史.
科学领域:
- 在瘤学瘤学.
- 肝病学 肝病学是一种肝病学.
- 病理学 病理学 病理学
背景情况:
- 从转移性黑色素瘤引起的急性肝衰竭 (ALF) 是罕见的,并且经常被误诊.
- 它可以模仿像Budd-Chiari综合征这样的肝脏紧急情况,特别是没有已知的癌症史.
- 及时识别对于移植候选人来说至关重要,以避免错误的管理.
研究的目的:
- 突出了透性黑色素瘤引起的ALF的诊断挑战.
- 强调在无法解释的ALF病例中考虑黑色素瘤的重要性.
- 审查类似的病例,并确定常见的诊断陷和结果.
主要方法:
- 一个61岁的男性患有不明原因的ALF的案例介绍.
- 诊断工作包括肝脏成像和活检.
- 对12起类似案件的回顾性审查.
主要成果:
- 活检揭示了黑色素瘤细胞 (黑色素瘤阳性) 对肝脏的广泛透.
- 这位患者以前没有癌症病史; 膜黑色素瘤被追溯怀疑.
- 患者病情迅速恶化并死亡;类似的病例显示出不良结果和频繁的错误诊断.
结论:
- 在不明原因的ALF中必须考虑透性黑色素瘤.
- 诊断是具有挑战性的,特别是当没有已知的先前恶性瘤时.
- 早期识别对于可能改善患者的治疗结果至关重要.
相关概念视频
Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...
Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...


