睡眠呼吸暂停和随后的尿失禁诊断之间的关系中的性别相关差异
Lara Ilona Becker1, Céline Vetter2, Karel Kostev1,2
1Department of Gynecology and Obstetrics, University Hospital, Philipps-University Marburg, Baldingerstraße, 35043 Marburg, Germany.
Clocks & sleep
|November 24, 2025
概括
睡眠呼吸暂停与尿失禁有关,特别是在中年妇女身上. 在男性中没有发现任何显著的关联. 进一步的研究应该考虑睡眠呼吸暂停患者的性别和年龄差异.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 睡眠呼吸暂停因其系统性影响而越来越受认可.
- 以前的研究表明,睡眠呼吸暂停和泌尿系统问题之间存在联系.
- 尿失禁是一种常见的尿道症状,具有重大影响.
研究的目的:
- 调查睡眠呼吸暂停和随后的尿失禁诊断之间的关系的性别特异性.
- 分析这种关联中与年龄相关的变化.
主要方法:
- 一项匹配对队列研究,涉及74,453名睡眠呼吸暂停患者和372,256名来自德国普通诊所的对照 (2005-2022年).
- 卡普兰-梅尔曲线和日志排名测试评估了五年内尿失禁的累积发病率.
- 进行了不变的考克斯回归和按性别和年龄组进行分层分析.
主要成果:
- 睡眠呼吸暂停与尿失禁有显著的关联 (5.1%对4.3%,p < 0.001).
- 这种关联在女性中是强大的 (HR:1.38),但在男性中没有 (HR:1.02).
- 在女性中,在51-60岁年龄组观察到最强的关联 (HR: 1.98).
结论:
- 睡眠呼吸暂停和随后的尿失禁之间存在显著的关联.
- 性别和年龄是关键因素,中年和年轻女性的相关性更强.
- 这些发现突显出需要针对睡眠呼吸暂停患者针对尿失禁风险进行量身定制的临床考虑.
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