相关实验视频

Updated: Jan 10, 2026

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia

Published on: March 5, 2018

在儿童骨髓移植单位实施早期流动性倡议

Anne Swanson^1,2, Kylie James^1,2, Kimberly Fan^1,3

¹St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Pediatric reports

|November 24, 2025

概括

这项研究旨在增加儿科造血细胞移植 (HCT) 接受者,包括扩展光谱β-乳糖酶 (ESBL) 定居者的出行率. 干预措施并没有显著增加患者的行走,在倡议之前观察到更多的运动.

科学领域:

儿科血液学儿科血液学
在瘤学瘤学.
传染病控制和控制传染病
康复医学康复医学康复医学

背景情况:

儿童造血细胞移植 (HCT) 接受者由于复杂的临床过程而面临功能障碍.
早期动员对于减少这些患者的长期功能问题至关重要.
感染传播问题,特别是扩展光谱β-乳糖酶 (ESBL) 殖民,可能会限制早期出行.

研究的目的:

在三个月内显著增加儿科HCT接受者的出行.
为了增强每天的行走活动,每周进行物理治疗 (PT) 访问,每次PT会话步行距离.

主要方法:

从电子健康记录中追溯收集数据 (2022年1月至10月).
实施一项质量改善计划,允许ESBL殖民患者带有个人防护设备 (PPE) 走动.
针对调动ESBL殖民患者的最新协议进行临床工作人员培训.

主要成果:

干预前的出行率高于干预后的出行率 (第一组:增加1.36倍,p=0.004;第二组与第三组:增加1.33倍,p=0.016).
对于行走变化的效果大小是适度的 (0.3042和0.2856).
这项干预措施未能实现其主要目标,即增加出行人数.

结论:

质量改善计划未能增加儿科HCT接受者的出行率.
观察到的行走趋势有利于干预前的时期,尽管统计能力有限.
短暂的监测,回顾性设计,个人防护设备挑战和未测量的变量等因素可能解释了缺乏成功.

关键词:

这是一种行走,行走.扩展光谱β-lactamase的使用情况.血细胞移植是血细胞的移植.住院治疗住院治疗动员动员动员动员儿科儿科儿科康复康复康复康复康复康复

更多相关视频

Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease

Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease

Published on: March 17, 2020

Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis

Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis

Published on: November 10, 2023

相关概念视频

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...

Differentiation of Common Myeloid Progenitor Cells

Differentiation of Common Myeloid Progenitor Cells

Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...