在老年人中使用nexobrid

Alexander Lugilde Guerbek¹, Jordi Serracanta Domenech¹, Antonio Bulla¹

¹Vall d'Hebron Burns Unit, Plastic Surgery Department, 08035 Barcelona, Spain.

European burn journal

|November 24, 2025

概括

用Nexobrid (NXB) 进行的酶去除可以在老年烧伤患者中安全地去除,防止隔间综合征. 虽然通常仍然需要移植,但NXB优化了伤床,以在这个高风险群体中获得更好的结果.

科学领域:

烧伤护理烧伤护理
老年医学老年医学
伤口愈合治愈伤口愈合

背景情况:

使用Nexobrid (NXB) 的酶解是一种公认的烧伤护理治疗方法.
在老年患者 (≥65岁) 中,NXB的结果没有得到充分的记录.
本研究评估了NXB在这个特定的人群中的安全性和有效性.

研究的目的:

评估Nexobrid (NXB) 对于老年烧伤患者 (≥65岁) 的酶解体的安全性和有效性.
在这个人群中描述与NXB治疗相关的临床结果,包括并发症和愈合时间.

主要方法:

对43名老年患者 (平均年龄为74.5岁) 进行了回顾性病例系列分析,这些患者有深度部分到全厚的烧伤.
收集的数据包括人口统计,烧伤特征,NXB治疗细节和并发症.
分析的重点是脱皮面积,切除骨头的需要,移植要求,死亡率和痕.

主要成果:

NXB应用于平均7.41%的TBSA,主要是在四肢和手上.
在NXB治疗的区域中不需要进行骨髓切割; 76.7%的患者最终需要手术自移植.
死亡率为25.6%,低于预期,平均修订后的宝克斯分数为90. 在28.1%的幸存者中出现过度缩性痕,中位愈合时间为63天.

结论:

尼克索布里德 (NXB) 在老年烧伤患者中表现出强烈的安全性,有效地去除骨和预防隔间综合征.
这一年龄组的主要好处是优化伤床用于移植,而不是减少手术干预.
虽然NXB是有益的,但与年龄相关的延迟愈合意味着随后的移植通常是必要的.

关键词:

这就是Nexobrid.年长的老人老年人老年人.经验经验经验经验经验经验经验

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