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膀瘤通过尿道切除的安全性:一个NSQIP分析
Jonathan J Song1, Maya T Zhou1, Samuel Z Lee1
1Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
World journal of urology
|November 24, 2025
概括
经历过尿道切除膀瘤 (TURBT) 的八胞胎患者面临更高的30天后严重术后并发症的风险,包括败血性休克和死亡. 对这个年龄组来说,精心的手术前咨询和出院计划是必不可少的.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 老年人手术是一门老年手术.
- 手术瘤学手术瘤学
背景情况:
- 膀瘤通过尿道切除 (TURBT) 是膀癌的标准程序.
- 老年患者,特别是八十岁以上 (≥80岁) 患者,可能对手术结果有不同的风险概况.
- 了解80岁以上人群的术后并发症率对于优化护理至关重要.
研究的目的:
- 为了比较80多岁患者和年轻患者之间TURBT的30天术后并发症率.
- 为了确定特定的并发症,这些并发症在 TURBT 后在老年人中更为普遍.
- 为了告知临床决策和患者咨询有关老年人TURBT.
主要方法:
- 从2012年到2022年对国家外科质量改进计划 (NSQIP) 数据库的回顾性审查.
- 包括接受 TURBT 作为主要手术的患者,不包括患有扩散癌症,败血症或呼吸机依赖的患者.
- 多变量逻辑回归分析,以评估年龄 (≥80 vs <80岁) 与30天术后并发症之间的关联,以混因子进行调整.
主要成果:
- 在78,665例TURBT病例中,27.5%是年龄≥80.5岁的患者.
- 八分生有明显更高的感染性休克 (aOR 2.29),在72小时内输血 (aOR 1.42),长时间住院 (aOR 1.50),再入院 (aOR 1.26) 和死亡 (aOR 2.74) 的几率.
- 八十岁以上的人群中,血和严重并发症 (Clavien-Dindo 3-5级) 的再入院率更高.
结论:
- 经过TURBT的八分生殖器体验了几种严重的30天后术后并发症的增加率.
- 尽管整体并发症率较低,但特定不良事件的风险增加需要考虑.
- 临床医生应该意识到这些增加的风险,在八十多岁的患者中进行手术前咨询和出院计划.
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