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Updated: Jan 6, 2026

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MPP+ 障碍 Irg1-Itaconate 轴通过激活顺丁酸脱酶来促进微质的 M1 极化

Lin-Yu Wang1, Yi-Yun Tang2,3, Wei Zou1,3,4

  • 1The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, 336 S Dongfeng Road, Hengyang, 421002, Hunan, People's Republic of China.

Molecular biology reports
|November 24, 2025
PubMed
概括

帕金森病的神经炎症涉及微质M1极化. MPP+治疗破坏了Irg1-Itaconate轴,激活SDH并促进M1极化,提供了一个治疗点.

关键词:
在Irg1-Itaconate轴上微质细胞中的微质细胞微质质的两极分化帕金森病的疾病.Succinate 脱水酶 的作用.

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