纹身是否会增加皮肤黑色素瘤的风险? 一个基于人口的病例控制研究
Emelie Rietz Liljedahl1,2, Kari Nielsen3,4, Malin Engfeldt5,6
1Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden. emelie.rietz_liljedahl@med.lu.se.
European journal of epidemiology
|November 24, 2025
概括
纹身可能会增加患皮肤黑色素瘤 (CM) 的风险. 这项研究发现,纹身患者中CM的相对风险增加了29%,这表明纹身可能是危险因素.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 在过去的30年里,皮肤黑色素瘤 (CM) 发病率显著增加.
- 纹身的受欢迎程度急剧上升,目前瑞典20%的人口有纹身.
- 人们对纹身油墨中的致癌化学物质存在担忧,包括多芳香碳化合物,芳香胺和重金属.
研究的目的:
- 调查纹身暴露与患皮肤黑色素瘤的风险之间的潜在关联.
- 为了确定纹身是否是CM的风险因素.
主要方法:
- 使用瑞典国家癌症登记册进行了一项病例控制研究.
- 2880名被诊断患有CM的个人 (20-60岁) 被确定为病例.
- 从瑞典总人口登记册中选择了三个年龄和性别匹配的对照组.
- 关于纹身暴露和混因素的数据是通过2021年问卷收集的.
- 使用多变量逻辑回归来估计纹身与未纹身个体中CM的相对风险.
主要成果:
- 22%的CM病例有纹身,而对照组只有20%.
- 与没有纹身的人相比,在纹身的人群中观察到CM的1.29 (95% CI:1.07-1.56) 的调整后相对风险 (IRR).
- 这表明与纹身相关的CM风险增加了29%.
结论:
- 纹身暴露可能是皮肤黑色素瘤的危险因素.
- 需要进一步的研究来确定纹身和CM之间的确切因果关系.
- 关于纹身相关的潜在风险的公共卫生意识可能是有必要的.
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