风湿性关节炎患者的预后营养指数和肉类之间的相关性
Xiaowei Shi1, Yingfang Wang1, Li Hua1
1Department of Rheumatology and Immunology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, Zhejiang, China.
British journal of hospital medicine (London, England : 2005)
|November 24, 2025
概括
预后营养指数 (PNI) 是一种有价值的工具,用于识别风湿性关节炎 (RA) 患者的萨科佩尼亚风险. 较低的PNI分数表明风险更高,可以进行早期干预以获得更好的结果.
科学领域:
- 类风湿病学 类风湿病学
- 老年学是一门学科.
- 营养科学 营养科学
背景情况:
- 类风湿性关节炎 (RA) 经常与营养不良和麻症有关,对患者的预后产生负面影响.
- 预后营养指数 (PNI) 由血清白蛋白和淋巴细胞计数得出的,反映了营养和炎症状况.
- 评估 RA 患者中 PNI 和肉症之间的关系对于改善患者管理至关重要.
研究的目的:
- 为了评估预后营养指数 (PNI) 与类风湿性关节炎 (RA) 患者的肉症之间的关联.
- 确定PNI在识别RA个体中的肉症的诊断实用性.
- 探索PNI在预测RA中与肉症相关的不良预后方面的作用.
主要方法:
- 在2023年6月至2025年6月期间住院的178名RA患者的回顾性分析.
- 根据2019年亚洲肉病工作组 (AWGS) 标准进行肉病诊断.
- 统计分析包括单变量/多变量逻辑回归和ROC曲线分析,以评估PNI的关联和诊断性能.
主要成果:
- 在178名RA患者中,有56名患者 (31.5%) 诊断出了沙尔科佩尼亚.
- 较低的PNI是肉症的一个独立风险因素 (OR=0.88,p=0.007).
- 一个结合年龄,PNI,疾病持续时间和CRP的预测模型显示了高准确度 (AUC=0.92) 检测.
结论:
- 预后营养指数 (PNI) 作为一种简单的,具有成本效益的标志物,用于识别患有沙尔科佩尼亚风险的RA患者.
- 普尼集成了营养和炎症标志物,有助于早期风险分层.
- 基于PNI评估的及时干预可能有助于改善沙科白病风险的RA患者的治疗结果.
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