大麻素过度复杂综合征,2016年至2022年
James A Swartz1, Dana Franceschini1
1Jane Addams College of Social Work, University of Illinois Chicago, Chicago.
JAMA network open
|November 24, 2025
概括
在COVID-19大流行期间,大麻素过度受精综合征 (CHS) 紧急诊所的访问量急剧增加,并且仍然很高. 这凸显了在临床实践中提高对CHS的认识和改善诊断的需要.
科学领域:
- 紧急医疗 紧急医疗
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 由于长期使用大麻而导致的反复吐的特征,大麻类高缩综合征 (CHS) 在急诊室 (ED) 越来越普遍.
- 关于CHS患病率,时间趋势和社会人口统计学关联的人口层面数据有限,阻碍了有效的公共卫生干预.
- 了解这些因素对于管理医疗保健机构中CHS日益增长的负担至关重要.
研究的目的:
- 估计2016年至2022年美国急诊室中CHS的流行率.
- 在此期间分析CHS发病率的时间趋势.
- 为了确定与CHS访问相关的社会人口统计因素.
主要方法:
- 一项采用全国急救部门样本 (NEDS) 数据的横截面研究,约占美国ED访问的85%.
- 分析包括12岁及以上的患者,不包括与怀孕,胃衰竭或化疗有关的访问.
- 紧急救护访问被分类,并使用受限立方线建模时间趋势,而多项物流回归确定了CHS的社会人口统计相关性.
主要成果:
- 这项研究分析了超过1.88亿次未加权的急救诊所访问.
- CHS患病率从2016年的每10万访客4.4个显著增加,在2020年第二季度达到33.1个,并在2022年保持在每10万访客22.3个的高度.
- 年轻的成年人 (18-35岁) 患CHS的风险最高,而美国南部的女性和个人与东北部相比风险较低.
结论:
- 美国ED的CHS患病率急剧增加,与COVID-19流行病相吻合,并且一直保持在高位.
- 这些发现强调了持续监测的重要性,以及需要完善CHS的临床识别和管理策略.
- 进一步研究CHS的潜在原因和有效治疗方法是有必要的.
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