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Updated: Jan 10, 2026

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味觉功能障碍和口腔虚弱:对阿尔茨海默病的新兴影响
Francesco Panza1, Madia Lozupone2, Emanuela Resta3
1"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari "Aldo Moro", Bari, Italy.
Journal of Alzheimer's disease : JAD
|November 24, 2025
概括
与年龄相关的味道变化和口腔虚弱与认知能力下降和阿尔茨海默病 (AD) 的更高风险有关. 解决这些感官和口腔健康问题可能有助于预防和管理AD.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 口腔健康 口腔健康
背景情况:
- 感官障碍,包括口味功能障碍,越来越多地与阿尔茨海默氏症 (AD) 等认知障碍有关.
- 与年龄相关的味道变化影响食欲,营养和口腔虚弱,这是一种涉及口腔结构和功能衰退的疾病.
- 口腔虚弱与身体和认知功能下降有关,对老年人的整体健康构成风险.
研究的目的:
- 审查口味功能障碍,口腔虚弱和阿尔茨海默病 (AD) 之间的复杂关系.
- 探索连接这些条件的潜在潜在机制.
- 突出感官和口腔健康在AD预防和管理中的重要性.
主要方法:
- 文献综述综合了关于味觉功能,口腔虚弱和AD的证据.
- 分析了在阿兹海默症患者和对照组中检查味道识别和认知状态的研究.
- 检查口腔健康指标 (牙周病,牙脱落) 与认知衰退之间的关联.
主要成果:
- 在阿尔茨海默病患者中,口味功能障碍与认知缺陷严重程度相关,在阿尔茨海默病患者中观察到口味识别受损 (尤其是酸味).
- 与轻度认知障碍患者相比,AD患者的味道识别得分较差.
- 口腔虚弱的指标,如牙周病和牙减少,始终与认知障碍和痴呆症有关,特别是AD.
结论:
- 味觉功能障碍和口腔虚弱可能会通过诸如大脑缩或对心理健康的影响等机制导致认知障碍和AD风险.
- 维护感官和口腔功能对于制定阿尔茨海默病预防,早期诊断和全面患者护理策略至关重要.
- 了解这些相互联系对于对阿尔茨海默症有风险或被诊断为阿尔茨海默症的个体进行整体管理至关重要.
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