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Updated: Jan 10, 2026

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KRAS突变如何破坏内在GTP水解:实验和计算调查

Lin Frank Song1, Dana Rabara2, Semiha K Bali1

  • 1Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94551, United States.

Journal of chemical information and modeling
|November 24, 2025
PubMed
概括

瘤性KRAS突变阻碍了GTP水解,这是癌细胞生存的关键过程. 了解这些突变对于开发有效的针对KRAS的癌症疗法至关重要.

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