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Updated: Jan 10, 2026

G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay
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Published on: September 10, 2016

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基于BRET的G蛋白生物传感器用于测量活细胞中的G蛋白结合受体活性

Adeline Cœugnet1, Hannes Schihada2, Estelle Rascol1

  • 1CNRS, Bordeaux INP, CBMN, UMR, University of Bordeaux.

Journal of visualized experiments : JoVE
|November 24, 2025
PubMed
概括

G蛋白结合受体 (GPCRs) 是细胞信号传递的关键. 新的G-CASE生物传感器使用生物发光共振能量转移 (BRET) 进行敏感的实时GPCR活动监测,帮助药物发现.

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