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Updated: Jan 10, 2026

Deciphering the Molecular Mechanism and Function of Pore-Forming Toxins Using Leishmania major
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ATR是一种DNA损伤激酶,它调节了Leishmania major中DNA复制时间

Gabriel L A da Silva1, Jeziel D Damasceno1, Jennifer A Black2

  • 1University of Glasgow Centre for Parasitology, The Wellcome Centre for Integrative Parasitology, University of Glasgow, School of Infection and Immunity, Glasgow, United Kingdom.

PLoS genetics
|November 24, 2025
PubMed
概括

这种阿塔克西亚-长长生病和Rad3相关的 (ATR) 蛋白质对于维持大莱什马尼亚的基因组稳定性至关重要. 它的C端删除破坏了DNA复制时间,并促进了染色体的不稳定性.

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