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运动抑制DEAF1,使mTORC1活动正常化并逆转肌肉衰老

Sze Mun Choy1, Kah Yong Goh1, Wen Xing Lee1

  • 1Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore.

Proceedings of the National Academy of Sciences of the United States of America
|November 24, 2025
PubMed
概括

衰老的肌肉功能障碍与过度活跃的mTORC1.1有关. 研究人员发现DEAF1驱动这种过度激活,但运动可以抑制DEAF1,恢复肌肉健康和功能.

关键词:
自自是自的过程.在 mTORC1 的情况下,mTORC1 是肌肉 肌肉 肌肉 肌肉 肌肉蛋白质稳定症是一种蛋白质稳定症.这种类型的麻症是sarcopenia.

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