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Updated: Jan 10, 2026

Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells
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Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells

Published on: November 1, 2017

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具有不同的起源,克隆系命运,转录组和表面标记的多能祖先产生了两个造血树

Fuwei Shang1,2, Tamar Nizharadze3,4, Robin Thiele1,4

  • 1Division of Cellular Immunology, German Cancer Research Center, Heidelberg 69120, Germany.

Proceedings of the National Academy of Sciences of the United States of America
|November 24, 2025
PubMed
概括

成年人造血症涉及两个不同的多能原始体 (MPP) 系统:胚胎MPP (eMPP) 和HSC衍生的MPP (hMPP). eMPP对早期的淋巴细胞发育有显著的贡献,而hMPP则在一生中支持髓状细胞系.

关键词:
条码编码 条码编码绘制命运地图,绘制命运的地图血液形成的不同层.干细胞和原生细胞.表面标记物识别标记物

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