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Updated: Jan 10, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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由N-hydroxynaphthalimide Ester启用的生物相容的脱碳酶化合

Hongze Liao1, Zhiyou Su1, Jia Zhang1

  • 1Department of Pharmacy, Ren Ji Hospital, College of Clinical Pharmacy, State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Nature communications
|November 24, 2025
PubMed
概括

这项研究引入了一种新的无催化剂,光诱导的反应,使用N-hydroxynaphthalimide Ester进行有效的Csp3-Csp3合. 这种方法使生物系统,包括活细胞中的化学修饰成为可能.

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