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Updated: Jun 20, 2026

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GlycoGenius:一个精简的高通量甘氨酸组合识别工具

Hector F Loponte1,2,3, Jing Zheng4, Yajie Ding4

  • 1Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands. hectorfloponte@gmail.com.

Nature communications
|November 24, 2025
PubMed
概括

GlycoGenius提供了自动化糖性成分数据分析,简化了复杂的质谱数据. 这种开源工具减少了人工工作,使研究人员能够更快地识别和量化甘氨酸.

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相关概念视频

Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...